When is the submission deadline?

Submissions are due November 30, 2026. Questions must be submitted by November 2, 2026.

It was issued by Advanced Research Projects Agency for Health. The work is located in Washington, District of Columbia, United States.

Simulation-Augmented Real-Time Platform (Due November 30, 2026)

Overview

Healthcare Services, Wellness & Biotech

Washington, District of Columbia, United StatesPosted: October 1, 2026Deadline: November 30, 2026

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SUMMARY

The organization is seeking a vendor to develop a persistent, simulation-augmented real-time platform for managing concurrent interventions and multi-phase operations. The solution must support adaptable documentation, governance, and the systematic reuse of operational and scientific learning.

KEY REQUIREMENTS

Must have an active registration in the System for Award Management (SAM.gov)
Must possess a Unique Entity Identifier (UEI)
Must be able to establish a multi-site clinical network and open the first site to enrollment no later than program year 2
Must include experienced project managers and experts in biostatistics, regulatory affairs, clinical medicine, AI and predictive modeling, and clinical operations
Must include at least three drug or biologic intervention arms
Must include at least two for-profit drug or biologic sponsors, including at least one startup or small company
Must include at least six clinical sites by the end of the program
Must demonstrate the ability to sustain the proposed platform trial after the SURPASS program is completed
Must provide documentation of current Assurance of Compliance with federal regulations for human subjects protection

CONTRACT DURATION

60 months

TIMELINE

Informational Webinar: October 15th, 2026

Proposers' Day: November 6th, 2026 and November 9th, 2026

Questions Due: November 2nd, 2026

Solution Summary Due Date: November 30th, 2026

Solution Pitch Package Due Date: January 22nd, 2027

Solution Pitches: February 1st, 2027 to February 5th, 2027

QUESTION DEADLINE

November 2, 2026

CONTACTS

Primary procurement contact — name, title, email, and phone

Additional decision-makers and their departments

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Issuing Agency

Advanced Research Projects Agency for Health

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DESCRIPTION

The issuing organization seeks a vendor to provide a simulation-augmented, real-time platform capable of supporting multiple simultaneous interventions under a common operational structure. The platform must preserve intervention-specific scientific, safety, regulatory, and statistical requirements while establishing platform-level processes, documents, data structures, and decision rules before the initial trial launch.

The platform should support concurrent intervention arms within a persistent, multi-phase framework. Regimen-, drug-, and arm-specific appendices and operational documents must be designed for efficient modification as new arms are added. The organization also requires a governance framework defining roles and responsibilities, decision rights, escalation pathways, and interfaces among the lead platform operator, sponsors, sites, functional departments, and vendors.

The proposed approach is intended to address repeated pauses and restarts in multi-phase, multi-stop operations, reducing the need to rebuild infrastructure and recruit control participants separately for each intervention. It should also enable clinical, statistical, regulatory, and operational learning to be carried forward systematically across phases and interventions.

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Frequently asked questions

When is the submission deadline?: Submissions are due November 30, 2026. Questions must be submitted by November 2, 2026.
Who issued this RFP?: It was issued by Advanced Research Projects Agency for Health. The work is located in Washington, District of Columbia, United States.
Who is a good fit for this opportunity?: Clinical trial technology and platform development expertise
Experience supporting adaptive, multi-arm, or platform-based trials
Strong capabilities in clinical, statistical, regulatory, and operational systems
Expertise designing governance frameworks and cross-functional workflows
Ability to support real-time data, simulation, and scalable infrastructure

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