When is the submission deadline?

Submissions are due September 22, 2026. Questions must be submitted by September 15, 2026.

It was issued by National Institutes Of Health. The work is located in Bethesda, Maryland, United States.

Who is a good fit for this opportunity?

Healthcare data platform and real-world data technology provider. Experience integrating electronic healthcare and clinical source systems. Expertise in data extraction, standardization, provenance, metadata, and ontology preservation. Ability to build modular, extensible systems supporting laboratory, pharmacy, imaging, archive, and specialty platforms. Experience supporting secure, permission-controlled access for research communities.

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Data Collect Once, Use Numerous Times System

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Overview

Data Analytics, AI & Cloud Hosting

Bethesda, Maryland, United StatesPosted: September 2, 2026Deadline: September 22, 2026

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SUMMARY

The agency is conducting market research for a modular system that extracts, standardizes, and preserves healthcare data for reuse in real-world data research. The solution must maintain source data, provenance, permissions, and ontology information while supporting multiple authorized healthcare systems.

KEY REQUIREMENTS

Must be able to attest to HIPAA Security Rule compliance as a Business Associate
Must provide a durable, Healthcare Partner Leave Behind Technology capability
Must support deep query for approved extraction from EMR systems
Must maintain an immutable provenance chain for all data
Must perform de-identification per 45 CFR §164.514(b)
Must provide Privacy Preserving Record Linkage (PPRL) tokenization capabilities
Must support TLS 1.3 or TLS 1.2 minimum for all data in transit
Must provide SIEM-compatible security logs
Must not include or permit contractor credentials or remote-access pathways

TIMELINE

Questions due by September 15th, 2026.

Responses due by September 22nd, 2026.

QUESTION DEADLINE

September 15, 2026

CONTACTS

Primary procurement contact — name, title, email, and phone

Additional decision-makers and their departments

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Issuing Agency

National Institutes Of Health

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DESCRIPTION

The agency is seeking information from vendors capable of providing a Data Collect Once, Use Numerous Times system to support its Real-World Data initiative. The capability is intended to provide high-quality, standardized data with preserved provenance and approved access for the research community.

Initially, the system will perform requested and approved data extraction from Healthcare Partner agency systems. It should be modular and extensible to support other authorized source systems, including laboratory information systems, pharmacy information systems, picture archiving and communication systems, vendor-neutral archives, and specialty systems.

The program requires preservation of source data and associated provenance metadata, permissions, and source ontology fields without modification or loss.

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Frequently asked questions

When is the submission deadline?: Submissions are due September 22, 2026. Questions must be submitted by September 15, 2026.
Who issued this RFP?: It was issued by National Institutes Of Health. The work is located in Bethesda, Maryland, United States.
Who is a good fit for this opportunity?: Healthcare data platform and real-world data technology provider
Experience integrating electronic healthcare and clinical source systems
Expertise in data extraction, standardization, provenance, metadata, and ontology preservation
Ability to build modular, extensible systems supporting laboratory, pharmacy, imaging, archive, and specialty platforms
Experience supporting secure, permission-controlled access for research communities

Analysis generated by Settle AI from the source RFP.

RFP Hunter shows what is open. Settle shows what is forming.

Settle pieces together buyer signals, budgets, contract activity, and the sources your team already monitors. See why an opportunity fits and what to do before the RFP posts.

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